Anti-Hu CD270 Purified

Product code: 30-2813

Clone name : CW10
Clonality : Monoclonal
Application : WB
Reactivity : Human

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0.1 mg
$398.00 

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Format : Purified
Amount : 0.1 mg
Purification : Purified by protein-A affinity chromatography.
Content : Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : TNFRSF14
Gene ID : 8764
Uniprot ID : Q92956
Alternative Name : TNF receptor superfamily member 14 TNFRSF14, TR2, ATAR, HVEA, HVEM, LIGHTR
Immunogen Information : recombinant human CD270

CD270 is a type I transmembrane protein of the TNFR superfamily, which is expressed on resting T cells, monocytes, and immature dendritic cells. Its ligands, CD258 and CD272, differ in effect on CD270 signaling. Whereas binding to CD258 provides a costimulatory signal, binding to CD272 gives to the cell an inhibitory signal. CD270 also is recognized by herpes simplex glycoprotein D. CD258-CD270 interaction and signaling is implicated in macrophage-derived foam cell-mediated development of atherosclerotic lesions.
Specificity :The mouse monoclonal antibody CW10 recognizes an extracellular epitope on CD270, a type I transmembrane protein expressed on resting T cells, monocytes, and immature dendritic cells.

Flow cytometry: Recommended dilution: 1-5 µg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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