Anti-Hu CD207 (Clone 2G3) Alexa Fluor 647

Flow cytometry surface staining pattern of stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD207 (2G3) Alexa Fluor 647 antibody (4 μl reagent per million cells in 100 μl of cell suspension, red-filled).

Anti-Hu CD207 (Clone 2G3) Alexa Fluor 647

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Flow cytometry surface staining pattern of stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD207 (2G3) Alexa Fluor 647 antibody (4 μl reagent per million cells in 100 μl of cell suspension, red-filled).

Figure 2: Flow cytometry multicolor surface staining of human stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD207 (2G3) Alexa Fluor 647 antibody (4 μl reagent per million cells in 100 μl of cell suspension) and anti-human CD11c (BU15) PE antibody (20 μl reagent per milion cells in 100 μl of cell suspension).

Figure 3: Separation of human CD11c positive CD207 positive differentiated dendritic cells (red-filled) from CD11c negative CD207 negative cell (black-dashed) in flow cytometry analysis (surface staining) of stimulated (GM-CSF + IL-4) peripheral blood mononuclear cells stained using anti-human CD207 (2G3) Alexa Fluor 647 antibody (4 μl reagent per million cells in 100 μl of cell suspension, red-filled).

Product code: 30-2927AF647

Clone name :	2G3
Clonality :	Monoclonal
Application :	FACS
Reactivity :	Human, Non-Human Primates

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For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 Tests
Isotype :	Mouse IgG1 lambda
Purification :	Purified by protein-A affinity chromatography.
Content :	Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition :	Store at 2-8°C. Do not freeze.


Gene :	CD207
Gene ID :	50489
Uniprot ID :	Q9UJ71
Alternative Name :	CLEC4K, langerin
Immunogen Information :	Fusion protein of human CD207 extracellular part and IgG Fc fragment

CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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