Anti-HSP47 Monoclonal Antibody (Clone : 1C4-1A6) - ATTO 700(Discontinued)

Product code: 42-1478

Clone name : 1C4-1A6
Clonality : Monoclonal
Application : WB, ICC/IF
Reactivity : Human
Conjugate : ATTO 700

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Amount : 200 µg
Isotype : Mouse IgG1 Kappa
Purification : Protein G Purified
Content : PBS pH7.4, 50% glycerol, 0.09% sodium azide
Storage condition : Store the antibody at 4°C
Gene : SERPINH1
Gene ID : 871
Uniprot ID : P50454
Alternative Name : SERPINH1, CBP1, CBP2, HSP47, SERPINH2, PIG14
Immunogen Information : Human HSP47, full length
HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils.

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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