Anti-HSP40, YDJ1 Monoclonal Antibody (Clone : 1G10.H8) - PE/ATTO 594(Discontinued)

Product code: 42-1339

Clone name : 1G10.H8
Clonality : Monoclonal
Application : WB, IP, ELISA
Reactivity : Yeast
Conjugate : PE/ATTO 594

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Amount : 100 µg
Isotype : Mouse IgG1 Kappa
Purification : Protein G Purified
Content : 50% glycerol, 0.09% sodium azide
Storage condition : Store the antibody at 4°C
Gene : YDJ1
Gene ID : 855661
Uniprot ID : P25491
Alternative Name : YDJ1, MAS5, YNL064C, N2418, YNL2418C
Immunogen Information : Full length protein yeast HSP40 (YDJ1)
Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of HSP40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not. Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1.

WB (1:2000); optimal dilutions for assays should be determined by the user.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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