Anti-HLA-G Monoclonal Antibody (Clone:87G)
Figure 1: Analysis of cytolytical activity of human polyclonal NK cells on target melanoma cells. Blocking of HLA-G1 on transfectants with anti-human HLA-G (87G) restored specific lysis. Target cells: M8 cell line transfected with empty vector (column 1) and with HLA-G1 cDNA (columns 2-6). Blocking antibodies: Column 1-2: none Column 3: Isotype mouse IgG2a control Column 4: anti-human HLA-G (87G) purified Column 5: anti-human HLA-G (87G) F(ab´)2 fragment Column 6: anti-human HLA-G (MEM-G/9; )
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2a |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Subcellular location: | Secreted |
| Tissue Specificity: | Expressed in trophoblasts. Expressed in fetal eye and thymus (PubMed:2336406). Also expressed in adult eye (PubMed:1570318). Isoform 4: Expressed in fetal first trimester trophoblasts (PubMed:7589701). Isoform 7: Expressed in first trimester, second trimester and term placenta, fetal liver, amniotic membrane, skin, cord blood and peripheral blood mononuclear cells (PubMed:11137219). |
| BioGrid: | 109380. 18 interactions. |
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