Anti-HLA-E PE (Clone : 3D12)

Product code: 30-2521

Clone name : 3D12
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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0.1 mg
$555.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : 0.1 mg/ml
Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : HLA-E
Gene ID : 3133
Alternative Name : HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E,major histocompatibility complex, class I, E
HLA-E (Human Leukocyte Antigen E) is a non-classical MHC I antigen, which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules, transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G, expression of HLA-E molecules is not so restricted, but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood, HLA-E protein is expressed at least in all mononuclear cells, but in different quantity (B cells and monocytes more than T cells and NK cells).
Specificity : The mouse monoclonal antibody 3D12 (also known as 3D12HLA-E) recognizes native extracellular part of HLA-E, an ubiquitously expressed non-classical MHC class I molecule, as well as free HLA-E.
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