Anti-HLA-DR Monoclonal Antibody (Clone:L243)-Low Endotoxin

Product code: 30-1647

Clone name : L243
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg
$398.00 

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Format : Low Endotoxin
Amount : 0.1 mg
Isotype : Mouse IgG2a
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : HLA-DRA
Gene ID : 3122
Uniprot ID : P01903
Alternative Name : HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA
Immunogen Information : Human B lymphocytes

HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system. It is expressed on antigen-presenting cells (dendritic cells, B lymphocytes, monocytes, macrophages).

Flow Cytometry Immunoprecipitation Western Blotting Immunohistochemistry Immunohistochemistry (frozen sections) Immunocytochemistry Functional Application blocking

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, Endosome, Lysosome
Post transnational modification: N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
BioGrid: 107410. 13 interactions.
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