Anti-HLA-Class I Monoclonal Antibody (Clone:W6/32)
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2a |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Gene : | HLA-A |
| Uniprot ID : | P01892 |
| Alternative Name : | HLA-A, HLAA |
| Immunogen Information : | Membrane of human tonsil cells |
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
Flow Cytometry Immunoprecipitation Western Blotting Application note: Non-reducing conditions. Immunohistochemistry (frozen sections) Immunocytochemistry ELISA Mass Cytometry Functional Application The antibody W6/32 is suitable as a positive control for HLA tissue typing.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, Endosome membrane, Lysosome membrane |
| BioGrid: | 109360. 40 interactions. |
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