Anti-HLA-Class I Monoclonal Antibody (Clone:MEM-123)

Product code: 30-1239

Clone name : MEM-123
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg
$398.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG3
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : HLA-A
Uniprot ID : P01892
Alternative Name : HLA-A, HLAA
Immunogen Information : COS-7 African green monkey kidney cells

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

Flow Cytometry Recommended dilution:4 µg/ml
Immunoprecipitation ELISA

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Membrane
Post transnational modification: Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).
BioGrid: 109360. 40 interactions.
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