Anti-HLA-B7 Monoclonal Antibody (Clone:BB7.1)

Product code: 30-1381

Clone name : BB7.1
Clonality : Monoclonal
Application : FACS
Reactivity : Human, Non-Human Primates

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0.1 mg
$398.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : HLA-B
Gene ID : 3106
Uniprot ID : P01889
Alternative Name : HLA-B, HLAB
Immunogen Information : Papain solubilised HLA-A2, B7
HLA-B7 allele of human HLA class I major histocompatibility (MHC) antigen indicates higher risk of breast cancer and cervical cancer. Expression of HLA-B7 together with HLA-B27 is associated with increased susceptibility to spondyloarthropaties. Flow cytometry detection of these two alleles is being used to screen for patients, who suffer from inflammatory disorders affecting the sacroiliac and intervertebral joints, such as ankylosing spondylosis (AS). The HLA-B7 antigen (11 alleles) is expressed in 22% of healthy Caucasian individuals.
Subcellular location: Membrane
Post transnational modification: Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).
BioGrid: 109351. 108 interactions.
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