Anti-Heregulin-1 / Neuregulin-1 (Breast and Urothelial Marker) Monoclonal Antibody(Clone: NRG1/2710)

Product code: 36-2468

Clone name : NRG1/2710
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $270.00 

  • $520.00 

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Amount : 100 µg
Isotype : Mouse IgG1, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : NRG1
Gene ID : 3084
Uniprot ID : Q02297
Alternative Name : Acetylcholine receptor-inducing activity (ARIA); Breast cancer cell differentiation factor p45; Glial growth factor (GGF2); Heregulin-1; Heregulin, alpha (45kD, ERBB2 p185-activator); HGL; HRG1; HRGA; MST131; Neu Differentiation Factor (NDF); Neuregulin-1; NRG1; Sensory and Motor Neuron-Derived Factor (SMDF)
Immunogen Information : Recombinant fragment of human Neuregulin-1 (NRG1) protein (around aa 21-242) (exact sequence is proprietary)

Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene throµgh alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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