Anti-HER-2 / c-erbB-2 / neu / CD340 Monoclonal Antibody(Clone: HRB2/258)-CF488
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Amount : | 0.5 ml at 100µg/ml |
Isotype : | Mouse IgG2a, kappa |
Content : | Antibody Purified from Bioreactor Concentrate by Protein A/G and conjµgated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format. |
Storage condition : | Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. |
Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. C-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood);Immunofluorescence (1:50-1:100);
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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