PE Conjugated, Anti-Helios Monoclonal Antibody (Clone:22F6)

Product code: 30-2385

Clone name : 22F6
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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Size
Price
100 tests
$503.00 

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Amount : 100 tests
Isotype : Hamster IgG
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : IKZF2
Gene ID : 22807
Uniprot ID : Q9UKS7
Alternative Name : IKZF2, HELIOS, ZNFN1A2
Immunogen Information : Peptide coresponding to the amino acids 51-107 of Helios

Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.

Subcellular location: Nucleus
BioGrid: 116485. 20 interactions.
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