Anti-GPN1 / XAB1 (DNA Repair & Protein Synthesis) Monoclonal Antibody (Clone: GPN1/2350)

Product code: 36-2083

Clone name : GPN1/2350
Clonality : Monoclonal
Application : ELISA, WB
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $270.00 

  • $520.00 

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Amount : 100 µg
Isotype : Mouse IgG1, kappa
Content : 200µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Gene : GPN1
Gene ID : 11321
Uniprot ID : Q9HN4
Alternative Name : ATP(GTP) binding protein (ATPBD1A); GPN-loop GTPase 1; GPN1; MBD2-interacting protein (MBDin); NTPBP; RNA polymerase II associated protein 4 (RPAP4); XPA-binding protein 1 (XAB1) GTPase
Immunogen Information : Recombinant full-length human GPN1 protein
GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.

ELISA (For coating, order antibody without BSA); Western Blot (1-2ug/ml);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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