Anti-GFAP (Astrocyte & Neural Stem Cell Marker) Recombinant Rabbit Monoclonal Antibody (Clone:ASTRO/1974R)

Product code: 12-1185

Clone name : ASTRO/1974R
Clonality : Monoclonal
Application : IHC, FACS, IF
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $270.00 

  • $520.00 

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A/G
Content : 200µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : GFAP
Gene ID : 2670
Uniprot ID : P14136
Alternative Name : Astrocyte or Intermediate Filament Protein, Glial Fibrillary Acidic Protein (GFAP)
Immunogen Information : Recombinant full-length human GFAP protein

This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.

Flow Cytometry (1-2µg/million cells);Immunofluorescence (2-3µg/ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: Phosphorylated by PKN1.
Tissue Specificity: Expressed in cells lacking fibronectin.
BioGrid: 108938. 98 interactions.
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