Anti-GARP / LRRC32 Monoclonal Antibody (Clone:GARP5)
Figure 1: Western Blotting analysis (reducing conditions) of GARP antigen and its degradatory products in lysate of human thrombocytes by anti-GARP monoclonal antibody (GARP5).
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
| Subcellular location: | Membrane |
| BioGrid: | 107658. 2 interactions. |
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