Anti-ETS1 (Marker of Tumor Metastasis) Monoclonal Antibody(Clone: ETS1/1801)
Fig. 1: SDS-PAGE Analysis Purified ETS1 Mouse Monoclonal Antibody (ETS1/1801). Confirmation of Integrity and Purity of Antibody.
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Shipping Info:
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| Amount : | 100 µg |
| Isotype : | Mouse IgG2b, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | ETS1 |
| Gene ID : | 2113 |
| Uniprot ID : | P14921 |
| Alternative Name : | Avian erythroblastosis virus E26 (v ets) oncogene homolog 1; ETS1; EWSR2; p54; v-ets erythroblastosis virus E26 oncogene homolog 1 |
| Immunogen Information : | Recombinant human ETS1 fragment (around aa137-230) (exact sequence is proprietary) |
ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.
ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA);
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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