Anti-ERCC1 / RAD10 (Tumor Progression Marker) Monoclonal Antibody(Clone: ERCC1/2683)

Name: Anti-ERCC1 / RAD10 (Tumor Progression Marker) Monoclonal Antibody(Clone: ERCC1/2683)
Brand: Abeomics
SKU: 36-2240
Price: 520.0000 USD
Availability: InStock
Rating: 4 (10 reviews)

Fig. 1: SDS-PAGE Analysis Purified ERCC1 Mouse Monoclonal Antibody (ERCC1/2683). Confirmation of Purity and Integrity of Antibody.

Anti-ERCC1 / RAD10 (Tumor Progression Marker) Monoclonal Antibody(Clone: ERCC1/2683)

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Fig. 1: SDS-PAGE Analysis Purified ERCC1 Mouse Monoclonal Antibody (ERCC1/2683). Confirmation of Purity and Integrity of Antibody.

Fig. 2: Analysis of Protein Array containing more than 19,000 full-length human proteins using ERCC1 Mouse Monoclonal Antibody (ERCC1/2683). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Product code: 36-2240

Clone name :	ERCC1/2683
Clonality :	Monoclonal
Application :	ELISA, WB
Reactivity :	Human

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Download TDS MSDS

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	ERCC1
Gene ID :	2067
Uniprot ID :	P07992
Alternative Name :	COFS4; DNA excision repair protein ERCC1; ERCC1; Excision repair cross complementing 1; RAD10; UV20
Immunogen Information :	Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)

Recognizes a protein of 110kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.

ELISA (For coating, order Ab without BSA); Western Blot (1-2ug/ml);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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