Anti-ER-beta-1 (Estrogen Receptor beta-1) Monoclonal Antibody(Clone: ESR2/3207)

Name: Anti-ER-beta-1 (Estrogen Receptor beta-1) Monoclonal Antibody(Clone: ESR2/3207)
Brand: Abeomics
SKU: 36-2258
Price: 520.0000 USD
Availability: InStock
Rating: 4 (10 reviews)

Fig. 1: SDS-PAGE Analysis Purified ER-beta Mouse Monoclonal Antibody (ESR2/3207). Confirmation of Purity and Integrity of Antibody.

Anti-ER-beta-1 (Estrogen Receptor beta-1) Monoclonal Antibody(Clone: ESR2/3207)

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Fig. 1: SDS-PAGE Analysis Purified ER-beta Mouse Monoclonal Antibody (ESR2/3207). Confirmation of Purity and Integrity of Antibody.

Fig. 2: Analysis of Protein Array containing more than 19,000 full-length human proteins using Estrogen Receptor beta-1 Mouse Monoclonal Antibody (ESR2/3207) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2258

Clone name :	ESR2/3207
Clonality :	Monoclonal
Application :	ELISA
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	ESR2
Gene ID :	2100
Uniprot ID :	Q92731
Alternative Name :	Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 (ER beta), estrogen receptor beta 4
Immunogen Information :	Recombinant full-length human ESR2 protein

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, thoÂµgh some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence sÂµggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even thoÂµgh they share many functional characteristics.

ELISA (For coating, order Ab without BSA);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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