Anti-DDIT4L Monoclonal Antibody (Clone:DDIT-03)
Figure 1: Western blotting analysis of DDIT4L expression in HEK293-DDIT4L transfectants and HEK293 cells using mouse monoclonal antibody DDIT-03.
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
| Subcellular location: | Cytoplasm |
| Tissue Specificity: | Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery. |
| BioGrid: | 125421. 10 interactions. |
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