Anti-DDIT4L Monoclonal Antibody (Clone:DDIT-03)-PE Conjugated
Figure 1: Flow cytometry detection of DDIT4L in DDIT4L-transfected Hek293 cells using the mouse monoclonal antibody DDIT-03 PE.
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Shipping Info:
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| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
| Subcellular location: | Cytoplasm |
| Tissue Specificity: | Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery. |
| BioGrid: | 125421. 10 interactions. |
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