Anti-CtBP1 / BARS Polyclonal Antibody
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Rabbit IgG |
| Purification : | Purified from rabbit serum by affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
C-terminal binding protein 1 / brefeldin A (BFA)-dependent ADP-ribosylation substrate (CtBP1/BARS) is a highly conserved transcriptional corepressor, that plays a critical role in regulating gene expression patterns throughout development and in oncogenesis. CtBP regulates target gene transcription, in part, via recruitment of histone deacetylases involved in gene silencing and may act to coordonate histone modifications that regulate gene expression.
Immunoprecipitation Western Blotting Application note: Reducing conditions.
Immunocytochemistry Recommended dilution: 1 µg/ml
Staining technique: acetone / methanol fixation
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus |
| Post transnational modification: | Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4. |
| Tissue Specificity: | Expressed in germinal center B-cells. |
| BioGrid: | 107869. 188 interactions. |
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