Anti-CD85g / ILT7 Monoclonal Antibody (Clone:17G10.2)
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD85g / ILT7 (Immunoglobulin-like transcript 7) is a cell surface protein that is expressed on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response, such as the TLR-induced interferon production. It associates with gamma subunit of the high-affinity IgE receptor to form a receptor complex which transduces the signal through ITAM-associated downstream molecules. Expression of CD85g is downregulated by interleukin 3.
Flow Cytometry Functional Application activation
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Tissue Specificity: | Detected on plasmacytoid dendritic cells (at protein level). Detected on plasmacytoid dendritic cells, but not on monocytes or B cells. |
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