Anti-CD80 Monoclonal Antibody (Clone:16-10A1)
Figure 1: FLOW analysis of Balb C mouse splenocytes stimulated with LPS (3 days) stained with purified CD80 (clone 16-10A1, red) or Armenian hamster IgG isotype control (green), followed by goat anti-Armenian hamster IgG PE.
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Hamster IgG2 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Immunogen Information : | CD80-transfected CHO cell line |
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Flow Cytometry Recommended dilution:6 µg/ml
Immunoprecipitation Immunohistochemistry (frozen sections) Functional Application Blocking
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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