Anti-CD70 Monoclonal Antibody (Clone:Ki-24)
Figure 1: Flow cytometry surface staining pattern of HUT-78 cells using anti- h CD70 purified antibody
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Shipping Info:
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG3 |
| Purification : | Purified by protein-A affinity chromatography |
| Content : | 1mg/ml, Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD70, also known as TNFSF7 or CD27L, is a 50 kDa type II transmembrane glycoprotein of the TNF superfamily. It is expressed mainly on activated lymphocytes, including NK cells, and forms trimeric structure. CD70 plays a role in T-cell activation, proliferation and differentiation, in enhancing the generation of cytolytic T cells, and in long-term maintenance of T cell memory. It is also involved in B cell differentiation induced by activated plasmacytoid dendritic cells, which also express CD70.
| Subcellular location: | Membrane |
| BioGrid: | 107408. 86 interactions. |
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