Anti-CD69 Monoclonal Antibody (Clone:FN50)-PE Conjugated
Figure 1: Surface staining of human PHA-activated peripheral blood using anti-CD69 antibody (clone FN50) PE.
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Shipping Info:
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| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.
| Subcellular location: | Membrane |
| Post transnational modification: | Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes. |
| Tissue Specificity: | Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. |
| BioGrid: | 107407. 9 interactions. |
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