Biotin Conjugated, Anti-CD64 / FcgammaRI Monoclonal Antibody (Clone:10.1)

Product code: 30-1904

Clone name : 10.1
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : Biotin

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price
0.1 mg
$433.00 

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Amount : 0.1 mg
Isotype : Mouse IgG1
Storage condition : Store at 2-8°C. Do not freeze.
Gene : FCGR1A
Gene ID : 2209
Uniprot ID : P12314
Alternative Name : FCGR1A, FCG1, FCGR1, IGFR1
Immunogen Information : Rheumatoid synovial fluid cells and fibronectin purified human monocytes

CD64 (FcgammaRI) is a cell surface receptor for Fc region of IgG. It is composed of specific ligand binding alpha subunit and promiscuous gamma subunit, which is indispensable for tyrosine-based signaling. However, even the alpha subunit can transduce signals leading to cellular effector functions. The isoform FcgammaRIa1 binds human IgG with high affinity, has limited myeloid cell distribution, and a relatively large intracellular domain. Products of related genes include FcgammaRIb and FcgammaRIc isoforms, but these specify low affinity IgG receptors if functionally expressed at all. Besides a role in antigen clearance, FcgammaRI (a1) can potently enhance MHC class I and II antigen presentation in vitro and in vivo.

Subcellular location: Cell membrane
Post transnational modification: Phosphorylated on serine residues.
Tissue Specificity: Monocyte/macrophage specific.
BioGrid: 108503. 20 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products