Anti-CD62L / L-selectin Monoclonal Antibody (Clone:LT-TD180)
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD62L (LT-TD180) purified antibody (concentration in sample 0.6 μg/ml) GAM APC.
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by precipitation and chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
| Subcellular location: | Cell membrane |
| Post transnational modification: | N-glycosylated. |
| Tissue Specificity: | Expressed in B-cell lines and T-lymphocytes. |
| BioGrid: | 112302. 13 interactions. |
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