Anti-CD59 / Protectin Monoclonal Antibody (Clone:MEM-43)

Product code: 30-1137

Clone name : MEM-43
Clonality : Monoclonal
Application : FACS
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price
0.1 mg
$389.00 

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG2a
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD59
Gene ID : 966
Uniprot ID : P13987
Alternative Name : CD59, MIC11, MIN1, MIN2, MIN3, MSK21
Immunogen Information : Thymocytes and T lymphocytes

CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.

Flow cytometry: Recommended dilution: 0.5-4 μg/ml.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml; positive tissue: placenta.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Secreted
Post transnational modification: Glycated. Glycation is found in diabetic subjects, but only at minimal levels in nondiabetic subjects. Glycated CD59 lacks MAC-inhibitory function and confers to vascular complications of diabetes.
BioGrid: 107404. 37 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products