Anti-CD58 / LFA-3 Monoclonal Antibody (Clone:MEM-63)-Biotin Conjugated

Product code: 30-1852

Clone name : MEM-63
Clonality : Monoclonal
Application : FACS
Reactivity : Pig
Conjugate : Biotin

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Size
Price
0.1 mg
$433.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD58
Gene ID : 965
Uniprot ID : P19256
Alternative Name : CD58, LFA3
Immunogen Information : NALM-6 human pre-B cell line

CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.

Subcellular location: Cell membrane
BioGrid: 107403. 13 interactions.
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