Anti-CD55 / DAF Monoclonal Antibody (Clone:MEM-118)-FITC Conjugated
Figure 1: Surface staining of human peripheral blood leukocytes by mouse monoclonal anti-CD55 antibody MEM-118.
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| Amount : | 100 tests |
| Isotype : | Mouse IgM |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
| Subcellular location: | Cell membrane |
| Post transnational modification: | The Ser/Thr-rich domain is heavily O-glycosylated. |
| Tissue Specificity: | Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix. |
| BioGrid: | 107974. 28 interactions. |
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