Anti-CD53 Monoclonal Antibody (Clone:MEM-53)-PE Conjugated

Product code: 30-2175

Clone name : MEM-53
Clonality : Monoclonal
Application : FACS, IP, WB, IHC-Fr, Functional Assay
Reactivity : Human
Conjugate : PE

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price
100 tests
$468.00 

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD53
Gene ID : 963
Uniprot ID : P19397
Alternative Name : CD53, MOX44, TSPAN25
Immunogen Information : Leukocytes of pacient suffering from a LGL-type leukemia.
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
Subcellular location: Cell membrane, Cell junction, Membrane
Tissue Specificity: B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.
BioGrid: 107401. 26 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products