Anti-CD47 / IAP (Integrin Associated Protein) Monoclonal Antibody(Clone: IAP/964 + B6H12.2)
Fig. 1: Immunofluorescence Analysis of PFA-fixed MCF-7 cells. CD47 Mouse Monoclonal Antibody (IAP/964 + B6H12.2) followed by goat anti-Mouse IgG-CF488 (Green). Nuclei are stained with Redot.
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| Amount : | 100 µg |
| Isotype : | Mouse IgG1, kappa + Mouse IgG1, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | CD47 |
| Gene ID : | 961 |
| Uniprot ID : | Q08722 |
| Alternative Name : | Antigenic Surface Determinant Protein OA3; IAP; Integrin Associated Protein; Integrin Associated Signal Transducer; MER6; OA3; Protein MER6; Rh Related Antigen |
| Immunogen Information : | Recombinant human IAP protein (IAP/964); Intact CD47 Purified from placenta (B6H12.2) |
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Functional Studies (Order Ab without Azide); Western Blot (1-2ug/ml); Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml);
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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