Anti-CD45RB Monoclonal Antibody (Clone:MEM-55)-APC Conjugated

Product code: 30-1695

Clone name : MEM-55
Clonality : Monoclonal
Application : FACS, IP, WB, IHC
Reactivity : Human, Non-Human Primates
Conjugate : APC

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100 tests
$468.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Immunogen Information : Human thymocytes and T lymphocytes.
CD45RB is an of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed e.g. in microglia and inflammatory cells.
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