Anti-CD45R Monoclonal Antibody (Clone:IHC536)

Product code: 44-1131

Clone name : IHC536
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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Available Pack Size(s)

  •   0.1 ml

  •  1 ml

  • $349.00 

  • $475.00 

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Format : Purified
Amount : 1 ml
Purification : Protein A/G Chromatography
Storage condition : Store at 2°C - 8°C.
Gene : PTPRC
Gene ID : 5788
Uniprot ID : P08575
Alternative Name : Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, CD45, L-CA, T200

CD45R, also known as MB1, is an isoform of CD45 that is a member of the protein tyrosine phosphatase (PTPase) family. CD45R is expressed specifically on the surface of hematopoietic cells, and has demonstrated function as a regulator of the antigen and cytokine receptor signalling of B and T cells. Given that the antigen is located in the membrane of all B cells, with the exception of plasma cells and some mature T cells, Anti-CD45R exhibits specific reactivity with most B lymphocytes. The use of Anti-CD45R is primarily useful in distinguishing B cell lymphomas from T cell lymphomas, with specific reactivity to follicle center cells, mantle cells, some medullary thymocytes, and 80% of B cell lymphomas.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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