Anti-CD42a Monoclonal Antibody (Clone:GR-P)-FITC Conjugated

Product code: 30-2104

Clone name : GR-P
Clonality : Monoclonal
Application : FACS
Reactivity : Human, Dog
Conjugate : FITC

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Price
100 tests
$433.00 

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Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : GP9
Gene ID : 2815
Uniprot ID : P14770
Alternative Name : GP9
Immunogen Information : Human acute lymphoblastic leukemia cells
CD42a, also known as Glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Subcellular location: Membrane
BioGrid: 109077. 20 interactions.
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