Anti-CD41 / Platelet GPIIb Monoclonal Antibody (Clone:MWReg30)
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Rat IgG1 |
| Purification : | Purified by protein-G affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Flow Cytometry Immunoprecipitation Immunohistochemistry Immunohistochemistry (frozen sections) ELISA Functional Application platelet depletion
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane |
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