Anti-CD41 / Platelet GPIIb Monoclonal Antibody (Clone:MWReg30)-PE Conjugated
Figure 1: Surface staining of CD41 on murine thrombocytes with anti-CD41 (MWReg30) PE.
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| Amount : | 0.1 mg |
| Isotype : | Rat IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
| Subcellular location: | Membrane |
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