Anti-CD35 / CR1 Monoclonal Antibody (Clone:E11)-FITC Conjugated
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD35 FITC antibody.
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| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD35 (complement receptor 1, CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes, monocytes, erythrocytes, B cells and folicular dendritic cells. Besides its role in complement cascade, CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.
| Subcellular location: | Membrane |
| Tissue Specificity: | Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. |
| BioGrid: | 107769. 1 interactions. |
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