Anti-CD300e / IREM-2 Monoclonal Antibody (Clone:UP-H2)-Low Endotoxin

Product code: 30-1652

Clone name : UP-H2
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg
$389.00 

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Format : Low Endotoxin
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD300E
Gene ID : 342510
Uniprot ID : Q496F6
Alternative Name : CD300E, CD300LE, CLM2, CMRF35A5, IREM2
Immunogen Information : CD300e-HA-transfected cells

CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.

Flow Cytometry Immunoprecipitation Western Blotting Functional Application stimulation

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Post transnational modification: N-glycosylated.
Tissue Specificity: Present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages (at protein level).
BioGrid: 131180. 8 interactions.
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