Anti-CD3 Monoclonal Antibody (Clone:SK7)-PE Conjugated(Discontinued)

Product code: 30-2142

Clone name : SK7
Clonality : Monoclonal
Application : FACS, WB, IHC-Fr, ICC
Reactivity : Human, Non-Human Primates
Conjugate : PE

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD3E
Gene ID : 916
Uniprot ID : P07766
Alternative Name : CD3E, T3E
Immunogen Information : Human thymocytes
CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.
Subcellular location: Cell membrane
Post transnational modification: Phosphorylated on Tyr residues after T-cell receptor triggering by LCK in association with CD4/CD8.
BioGrid: 107354. 25 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products