Anti-CD279 / PD-1 Monoclonal Antibody (Clone:EH12.2H7)-APC Conjugated

Product code: 30-1676

Clone name : EH12.2H7
Clonality : Monoclonal
Application : FACS, IHC-Fr, Functional Assay
Reactivity : Human, Non-Human Primates
Conjugate : APC

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Size
Price
100 tests
$468.00 

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Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : PDCD1
Gene ID : 5133
Uniprot ID : Q15116
Alternative Name : PDCD1, PD1
CD279 / PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its receptors CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis.
Subcellular location: Membrane
BioGrid: 111160. 61 interactions.
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