Anti-CD274 / PD-L1 Monoclonal Antibody (Clone:29E.2A3)-APC Conjugated

Product code: 30-1677

Clone name : 29E.2A3
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price
100 tests
$468.00 

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG2b
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD274
Gene ID : 29126
Uniprot ID : Q9NZQ7
Alternative Name : CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Immunogen Information : Full length human CD274

CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely.

Subcellular location: Endomembrane system
Post transnational modification: Ubiquitinated; STUB1 likely mediates polyubiquitination of PD-L1/CD274 triggering its degradation.
Tissue Specificity: Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
BioGrid: 118891. 48 interactions.
There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products