Anti-CD271 / NGFR Monoclonal Antibody (Clone:NGFR5)-PE Conjugated

Product code: 30-2296

Clone name : NGFR5
Clonality : Monoclonal
Application : FACS, IP, WB, IHC, ICC
Reactivity : Human, Non-Human Primates, Feline, Rabbit, Ferret
Conjugate : PE

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100 tests
$468.00 

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Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : NGFR
Gene ID : 4804
Uniprot ID : P08138
Alternative Name : NGFR, TNFRSF16
Immunogen Information : Purified CD271 protein isolated from human melanoma cell line A875
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
Subcellular location: Membrane
Post transnational modification: Phosphorylated on serine residues.
BioGrid: 110870. 37 interactions.
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