Anti-CD271 / NGFR Monoclonal Antibody (Clone:NGFR5)-APC Conjugated
Figure 1: Surface staining (flow cytometry) of REH cells with anti-CD271 (NGFR5) APC.
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| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
| Subcellular location: | Membrane |
| Post transnational modification: | Phosphorylated on serine residues. |
| BioGrid: | 110870. 37 interactions. |
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