Anti-CD27 Monoclonal Antibody (Clone:LT27)-PE/DyLight Conjugated

Product code: 30-2469

Clone name : LT27
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE/DyLight

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100 tests
$494.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG2a
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD27
Gene ID : 939
Uniprot ID : P26842
Alternative Name : CD27, TNFRSF7
Immunogen Information : Human peripheral blood lymphocytes
CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.
Subcellular location: Membrane
Post transnational modification: O-glycosylated with core 1 or possibly core 8 glycans.
Tissue Specificity: Found in most T-lymphocytes.
BioGrid: 107377. 32 interactions.
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