Anti-CD27 antibody(DM57), Rabbit mAb

Figure 1. Expi 293 cell line transfected with irrelevant protein (A) and human CD27 (B) were surface stained with Rabbit anti-CD27 monoclonal antibody 1µg/ml (clone: DM57) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.

Roll over image to zoom in

Figure 1. Expi 293 cell line transfected with irrelevant protein (A) and human CD27 (B) were surface stained with Rabbit anti-CD27 monoclonal antibody 1µg/ml (clone: DM57) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.

Figure 2. FACS data of serially titrated Rabbit anti-CD27 monoclonal antibody (clone: DM57) on Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Figure 3. Affinity ranking of different Rabbit anti-CD27 mAb clones by titration of different concentration onto Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Product code: 12-9044

Clone name :	DM57
Clonality :	Monoclonal
Application :	ELISA, FACS
Reactivity :	Human

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Write a review for this product on BioCompare

Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Rabbit IgG
Purification :	Purified from cell culture supernatant by affinity chromatography
Content :	Preservative: 0.1% Procline 300 Constituents: 50% Glycerol; PBS,pH 7.4; 0.1% BSA Not Sterile
Storage condition :	Store at -20°C for 12 months (Avoid repeated freezing and thawing)


Alternative Name :	CD27, TNFRSF7, S152, T14, Tp55
Immunogen Information :	Recombinant human CD27 (Ala20-Arg191) produced by using human HEK293 cells

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Recommended Dilutions ELISA 1/5000-10000;FACS 1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews

Write a review on this product!