Anti-CD267 / TACI Monoclonal Antibody (Clone:1A1)

Product code: 30-1081

Clone name : 1A1
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg
$389.00 

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For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 0.1 mg
Isotype : Rat IgG2a
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : TNFRSF13B
Gene ID : 23495
Uniprot ID : O14836
Alternative Name : TNFRSF13B, TACI
Immunogen Information : CD267-transfected RBL cells

CD267 / TACI (Transmembrane Activator Calcium modulator and cyclophilin ligand Interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.

Subcellular location: Membrane
Tissue Specificity: Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.
BioGrid: 117046. 36 interactions.
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