Anti-CD267 / TACI Monoclonal Antibody (Clone:1A1)-PE Conjugated

Product code: 30-2136

Clone name : 1A1
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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Price
100 tests
$468.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Rat IgG2a
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : TNFRSF13B
Gene ID : 23495
Uniprot ID : O14836
Alternative Name : TNFRSF13B, TACI
Immunogen Information : CD267-transfected RBL cells
CD267 / TACI (Transmembrane Activator Calcium modulator and cyclophilin ligand Interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.
Subcellular location: Membrane
Tissue Specificity: Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.
BioGrid: 117046. 36 interactions.
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