Anti-CD255 / TWEAK Monoclonal Antibody (Clone:CARL-1)-PE Conjugated

Product code: 30-2375

Clone name : CARL-1
Clonality : Monoclonal
Application : FACS, IHC, Functional Assay
Reactivity : Human
Conjugate : PE

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Price
100 tests
$468.00 

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Amount : 100 tests
Isotype : Mouse IgG3
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Immunogen Information : human CD255-transfected 2PK-3 cells
CD255 / TWEAK (TNF-related weak inducer of apoptosis), a type II transmembrane protein expressed as membrane-bound and secreted form, can induce apoptosis in many tissues and cell lines through its receptor CD266 / TWEAK R. On the other hand, in endothelial cells this interaction can induce proliferation and promote angiogenesis including neovascularization of tumours. CD255 can act in a juxtacrine manner to initiate cellular responses, and induces secretion of pro-inflammatory cytokines. Besides CD266, CD255 may also bind to DR3.
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